Research and Markets (http://www.researchandmarkets.com/research/lwwcrv/triptans) has announced the addition of the “Triptans (Migraine) – Forecast and Market Analysis to 2023″ report to their offering.
The migraine market is saturated with generic drugs, and the remaining branded products already on the market are expected to lose exclusivity during the next few years, with the exception of Botox for chronic migraine, which is expected to maintain its leading position in terms of sales. However, reformulations of mature products as well as new classes of therapies are anticipated to launch during the forecast period and these will contribute to the market growth.
By 2023, the migraine market will grow to $3.7 billion at a compound annual growth rate (CAGR) of 3.6%, with the US continuing to dominate the market as a result of higher drug prices and a large migraine population. Some of the new treatments are expected to target the key unmet needs but opportunities will remain for further treatment choices especially drugs that will offer an improved safety and side-effects profile.
Triptans are indicated for the acute treatment of a migraine attack once it has begun, as well as its associated symptoms such as photophobia, phonophobia and nausea. Triptans are selective serotonin (5-HT) receptor agonists that display high affinity for the 5-HT1 class of receptors. Specifically these are the 5-HT1B and 5-HT1D receptor subtypes, as well as some having varying affinity for the 5-HT1F receptor subtype. Each of the individual subtypes has a different mechanism of action. The 5-HT1B subtype causes vasoconstriction in the cranial circulation and in the heart, whereas 5-HT1D subtypes are located on CNS neurons and trigeminal nerve endings.
Key Topics Covered:
1 Table of Contents
3 Disease Overview
4 Disease Management
5 Competitive Assessment
For more information visit http://www.researchandmarkets.com/research/lwwcrv/triptans
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